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Reflections on "Transsexualism and Sex Reassignment" 1969 -1999 Panel: Transsexual Professionals: Their Area of Work and Research Interest Feminizing Hormone Regimens and Their Influence on Pro-Inflammatory Cytokines in Limiting and Preventing Congestive Heart Disease. Kirk, M.D., Sheila Surgeon TSMC Center, Pittsburgh, Pittsburgh, Pennsylvania, USA Recently studies have focused on a new and exciting group of neurohormonal substances-the proinflammatory cytokines and their role in the development of congestive heart failure. There is suggestion that estrogen may have an important effect on proinflammatory cytokine expression. The Transgender Surgical and Medical Center (TSMC) in Pittsburgh, Pennsylvania, USA has joined with the cardiology department of the University of Pittsburgh School of Medicine to look at the potential of elimination or reduction of another cardiovascular risk in genetic males using a feminizing hormone regimen. A protocol is in development and some of the expectations and planning is discussed in this brief presentation. |